Chinese Journal of Organic Chemistry >
Advances in the Collective Synthesis of Lycopodium Alkaloids
Received date: 2016-11-24
Revised date: 2016-12-24
Online published: 2017-01-17
Supported by
Project supported by the National Natural Science Foundation of China (Nos. 21403169, 21502153), the Postdoctoral Science Foundation of China (No. 2013M532084) and the Chinese Universities Scientific Fund (No. 2452015079).
In view of the relevance between chemical structures and biosynthetic pathways of compounds that belong to the same family of natural products, MacMillan et al. (2011) proposed a strategy for the rapid and efficient synthesis of natural product within a family from a common intermediate or a group of similar intermediates, which is termed as collective synthesis. In recent years, this strategy has been applied for the synthesis of multiple family of natural products. Lycopodium alkaloids are a class of structurally diverse alkaloids, and many of them exhibiting good biological activity. In this review, the progress in the collective synthesis of Lycopodium alkaloids is summarized.
Xiao Chunxia , Cao Lin , Wang Jia , Miao Yinlong , Fan Huafang . Advances in the Collective Synthesis of Lycopodium Alkaloids[J]. Chinese Journal of Organic Chemistry, 2017 , 37(4) : 810 -823 . DOI: 10.6023/cjoc201611032
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