Chinese Journal of Organic Chemistry >
Synthesis,Herbicidal Activities of Novel Triketone Compounds Containing 4-Substituted Cyclopentane-1,3-dione Moiety
Received date: 2017-04-24
Revised date: 2017-05-10
Online published: 2017-06-07
Supported by
Project supported by the National Natural Science Foundation of China (Nos.21072108,21372134).
To find new lead compounds with muti-bioactivities, a series of novel triketone derivatives containing 4-substituted cyclopentane-1,3-dione were designed on the base of various commercial products. The target compounds were synthesized from cyclopentane-1,3-dione in six steps. Their structures were confirmed by IR, 1H NMR spectra and HRMS. The preliminary greenhouse bioassay results indicated that some compounds showed obvious inhibition effects against Brassica campestris, and the inhibition rate was more than 80% at 100 μg/mL. In the pre-and post-emergence, some of them exhibited excellent herbicidal activities against Brassica campestris, and the herbicidal activity was more than 90% at 1500 g/ha.
Xu Haizhen , Xie Lifen , Han Tingfeng , He Jingli , Zhu Youquan . Synthesis,Herbicidal Activities of Novel Triketone Compounds Containing 4-Substituted Cyclopentane-1,3-dione Moiety[J]. Chinese Journal of Organic Chemistry, 2017 , 37(10) : 2717 -2724 . DOI: 10.6023/cjoc201704039
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