Chinese Journal of Organic Chemistry >
Secondary Metabolites of Endophytic Fungus Penicillium mariae-crucis from Paeonia lactiflora Pall
Received date: 2018-11-21
Revised date: 2019-01-04
Online published: 2019-01-31
Supported by
Project supported by the Special Guide for Local Science and Technology Development Guided by the Central Committee of Anhui Province (No.2017070702D173),the Anhui University of Chinese Medicine (Nos.2017HXTS31,2017HXTS2) and the State Key Laboratory of Phytochemistry and Plant Resources in West China (No.P2017-KF03).
Four new compounds, penicmariae-crucis A (1), penicmariae-crucis B (2), penicmariae-crucis C (3), penicmariae-crucis D (4), and a new natural product, (E)-2-methylhex-3-enedioic acid (5), together with five known compounds, O-methylcurvulinic acid (6), methyl 2-acetyl-3-hydroxy-5-methoxyphenylacetate (7), methyl 2-acetyl-3,5-dihydroxyphenyl-acetate (8), β-sitosterol (9) and ergosterol peroxide (10), were isolated from the ethyl acetate extract of endophytic fungus Penicillium mariae-crucis in Paeonia lactiflora Pall. Their structures were established on the basis of extensive spectral analyses. All known compounds were isolated from P. mariae-crucis for the first time.
Wang Jutaoa , Ma Zonghuia , Wang Guokaia , Xu Fengqinga , Yu Yang , Wang Ganga , Liu Jinsong . Secondary Metabolites of Endophytic Fungus Penicillium mariae-crucis from Paeonia lactiflora Pall[J]. Chinese Journal of Organic Chemistry, 2019 , 39(4) : 1136 -1141 . DOI: 10.6023/cjoc201811026
[1] Zhang, L.; Zhao, B. J.; Yuan, J. R.; Wang, C. F.; Feng, L.; Jia, X. B. China J. Chin. Mater. Med. 2016, 41, 1835(in Chinese).(章丽, 赵冰洁, 袁嘉瑞, 汪春飞, 封亮, 贾晓斌, 中国中药杂志, 2016, 41, 1835.)
[2] Shi, Y. M.S. Thesis, Shaanxi University of Science and Technology, Xi'an, 2015 (in Chinese).(石钰, 硕士论文, 陕西科技大学, 西安, 2015.)
[3] Wang, H. H.; Li, G.; Peng, X. P.; Lou, H. X. Acta Pharm. Sin. 2018, 53, 1(in Chinese).(王航航, 李刚, 彭晓娉, 娄红祥, 药学学报, 2018, 53, 1.)
[4] Chen, X. D. Microbiology (Beijing, China) 2012, 39, 282(in Chinese).(陈向东, 微生物学通报, 2012, 39, 282.)
[5] Hou, X. Q.; Guo, S. X. China J. Chin. Mater. Med. 2014, 39, 3232(in Chinese).(侯晓强, 郭顺星, 中国中药杂志, 2014, 39, 3232.)
[6] Liang, Y. M.; Yu, Y.; Sun, Y. P.; Liu, J. S.; Ma, Z. H.; Liu, H. T.; Wang, G. Nat. Prod. Res. Dev. 2018, 30, 783(in Chinese).(梁益敏, 郁阳, 孙云鹏, 刘劲松, 马宗慧, 刘海涛, 王刚, 天然产物研究与开发, 2018, 30, 783.)
[7] Cheng, X. Z.; Xu, Y.; Ge, Y. B.; Wei, L.; Yan, A. L.; Zhang, Y.; Liu, X. L.; Xu, J.; Guo, H. J. Anhui Agric. Sci. 2016, 44, 162(in Chinese).(程孝中, 许勇, 葛永斌, 魏磊, 燕傲蕾, 张宇, 刘西岭, 徐娟, 郭慧, 安徽农业科学, 2016, 44, 162.)
[8] Shaala, L. A.; Youssef, D. T. Mar. Drugs 2015, 13, 1698.
[9] Chou, T. H.; Chen, I. S.; Hwang, T. L.; Wang, T. Ch.; Lee, T. H.; Cheng, L. Y.; Chang, Y. C.; Cho, J. Y.; Chen, J. J. J. Nat. Prod. 2008, 71, 1692.
[10] Skehan, P.; Storeng, R.; Scudiero, D.; Monks, A.; McMahon, J.; Vistica, D.; Warren, J. T.; Bokesch, H.; Kenney, S.; Boyd, M. R. J. Natl. Cancer Inst. 1990, 82, 1107.
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