Chinese Journal of Organic Chemistry >
Tributylphosphine Catalyzed Cross Rauhut-Currier Reaction of Chalcones and Acrylates
Received date: 2019-04-08
Revised date: 2019-05-04
Online published: 2019-05-15
Supported by
Project supported by the National Natural Science Foundation of China (Nos. 21672109, 21871148, 21472097) and the Natural Science Foundation of Tianjin City (No. 15JCYBJC20000).
Rauhut-Currier (RC) reaction is an effective atom-economic method to construct C-C bond. However, the application of this reaction is limited by the lack of selectivity. Herein, an efficient intermolecular cross Rauhut-Currier reaction between chalcones and acrylates in the presence of the tributylphosphine catalyst was developed, the reactions were carried out in mild conditions, and performed well with a series of substrates, delivering the desired products with acceptable to good yields.
Key words： tributylphosphine; catalysis; Rauhut-Currier reaction; chalcone; acrylate
Gu Yingchun , Huang You . Tributylphosphine Catalyzed Cross Rauhut-Currier Reaction of Chalcones and Acrylates[J]. Chinese Journal of Organic Chemistry, 2019 , 39(8) : 2251 -2256 . DOI: 10.6023/cjoc201904017
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