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Chinese Journal of Organic Chemistry >

2019 , Vol. 39 >Issue 10: 2920 - 2929

DOI: https://doi.org/10.6023/cjoc201903073

ARTICLES

Synthesis of Pyrazolines by Cascade Oxidation/Halogenoamino-cyclization Reaction of Homoallylhydrazides

  • Pengfei Li, ,
  • Danfeng Huang, ,
  • Tianyu Yang, ,
  • Zhoubin Deng, ,
  • Kehu Wang, ,
  • Junjiao Wang, ,
  • Yingpeng Su, ,
  • Yulai Hu,
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  • College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070

Received date: 2019-03-29

  Revised date: 2019-04-26

  Online published: 2019-05-21

Supported by

Project supported by the National Natural Science Foundation of China(Nos. 21662030);Project supported by the National Natural Science Foundation of China(21861033)

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Abstract

An efficient cascade oxidation/halogenoaminocyclization reaction of homoallylhydrazides with N-halogensuc- cinimide was developed without addition of other additives under mild reaction conditions to provide pyrazolines. Under the optimized conditions, a variety of highly substituted pyrazoline derivatives were obtained.

Key words： oxidation/halogenoaminocyclization; pyrazolines; homoallylhydrazides; N-halogensuccinimide

Cite this article

Pengfei Li, , Danfeng Huang, , Tianyu Yang, , Zhoubin Deng, , Kehu Wang, , Junjiao Wang, , Yingpeng Su, , Yulai Hu, . Synthesis of Pyrazolines by Cascade Oxidation/Halogenoamino-cyclization Reaction of Homoallylhydrazides[J]. Chinese Journal of Organic Chemistry, 2019 , 39(10) : 2920 -2929 . DOI: 10.6023/cjoc201903073

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