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Chinese Journal of Organic Chemistry >

2019 , Vol. 39 >Issue 12: 3588 - 3593

DOI: https://doi.org/10.6023/cjoc201905028

Synthesis and Herbicidal Activity of Chiral Aryloxyphenoxypropionic Amides Compounds

  • Yang Sen ,
  • Ding Chengrong ,
  • Liu Xinghai ,
  • Weng Jianquan ,
  • Yuan Jing ,
  • Tan Chengxia
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  • a College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014;
    b College of Forestry and Biotechnology, Zhejiang Agriculture and Forestry University, Hangzhou 311300

Received date: 2019-05-13

  Revised date: 2019-06-03

  Online published: 2019-06-19

Supported by

Project supported by the National Key R & D Program (No. 2017YFD0200507).

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Abstract

In order to find pesticidal lead compounds with high herbicidal activity, a series of novel chiral aryloxyphenoxypropionic amides were designed and synthesized using the principle of active substructure combination and the technology of biological enzyme splitting. The structures of the target compounds were confirmed by 1H NMR and HRMS. The preliminary bioassay data showed that all target compounds displayed excellent herbicidal activity and selectivity against monocotyledonous weeds. At the dosage of 150 g/ha, the target compounds showed herbicidal activity against Backmannia syzigachne, Polypogon fugax and Poa acroleuca with more than 75%. And the control effects of three compounds against Polypogon fugax Nees were 100%.

Key words： aryloxyphenoxypropionic acids; herbicide; chirality; herbicidal activity; synthesize; enzyme splitting

Cite this article

Yang Sen , Ding Chengrong , Liu Xinghai , Weng Jianquan , Yuan Jing , Tan Chengxia . Synthesis and Herbicidal Activity of Chiral Aryloxyphenoxypropionic Amides Compounds[J]. Chinese Journal of Organic Chemistry, 2019 , 39(12) : 3588 -3593 . DOI: 10.6023/cjoc201905028

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