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Chinese Journal of Organic Chemistry >

2020 , Vol. 40 >Issue 5: 1297 - 1304

DOI: https://doi.org/10.6023/cjoc201911024

Coupling of Hantzsch Esters with Baylis-Hillman Derivatives via Visible-Light Photoredox Catalysis

  • Chen Yuefeng ,
  • Zhao He ,
  • Cheng Dongping ,
  • Li Xiaonian ,
  • Xu Xiaoliang
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  • a College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014;
    b College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014

Received date: 2019-11-19

  Revised date: 2020-01-17

  Online published: 2020-02-15

Supported by

Project supported by the Zhejiang Provincial Natural Science Foundation (Nos. LY18B020018, LY15B020004) and the National Natural Science Foundation of China (No. 21602197).

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Abstract

4-Alkyl Hasntzch esters are good alkyl radical storage. The preparation of multisubstituted α,β-unsaturated carboxylic acid esters under photocatalytic redox conditions by 4-alkyl Hantzsch esters and Baylis-Hillman adducts was investigated. The reaction conditions are mild and no additional additives are required. The coupling products were obtained in moderate to good yields.

Key words： visible light photocatalysis; radical addition; Baylis-Hillman adducts; 4-alkyl Hantzsch esters

Cite this article

Chen Yuefeng , Zhao He , Cheng Dongping , Li Xiaonian , Xu Xiaoliang . Coupling of Hantzsch Esters with Baylis-Hillman Derivatives via Visible-Light Photoredox Catalysis[J]. Chinese Journal of Organic Chemistry, 2020 , 40(5) : 1297 -1304 . DOI: 10.6023/cjoc201911024

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