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Chinese Journal of Organic Chemistry >

2020 , Vol. 40 >Issue 3: 589 - 597

DOI: https://doi.org/10.6023/cjoc201909032

Progress in C—N Bond Formation Involving C(sp2)—H Bond through Transition-Metal-Free Radical Reactions

  • Wu Yan ,
  • Chen Jinyang ,
  • Li Qiang ,
  • Wei Wenting
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  • a College of Chemistry and Chemical Engineering, Yangtze Normal University, Chongqing 408000;
    b School of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng, Shandong 252059;
    c School of Materials Science and Chemical Engineering, Ningbo University, Ningbo, Zhejiang 315211

Received date: 2019-09-22

  Revised date: 2019-10-26

  Online published: 2020-04-02

Supported by

Project supported by the Basic and Frontier Research Project of Chongqing (Nos. Cstc2018jcyjAX0721, Cstc2018jcyjAX0051), the Youth Talent Growth Plan Project of Yangtze Normal University (No. 2018QNRC11) and the Education Commission of Chongqing City (No. KJQN201801404).

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Abstract

The C-N bond is widely found in medicinal molecules, natural products and functional materials. Therefore, it has great significance to develop simple and efficient methods for the construction of C-N bond. Recently, remarkable progress has been made in construction of C-N bond involving C(sp2)-H bond through transition-metal-free radical reactions. Due to the relatively mild reaction condition and high reactivity, it provides a novel approach to construct C-N bond. In this review, the recent developments in this area are summarized on the basis of different nitrogen sources.

Key words： C—N bond; C (sp2)—H bond; transition-metal-free; radical

Cite this article

Wu Yan , Chen Jinyang , Li Qiang , Wei Wenting . Progress in C—N Bond Formation Involving C(sp2)—H Bond through Transition-Metal-Free Radical Reactions[J]. Chinese Journal of Organic Chemistry, 2020 , 40(3) : 589 -597 . DOI: 10.6023/cjoc201909032

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