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Chinese Journal of Organic Chemistry >

2020 , Vol. 40 >Issue 12: 4015 - 4030

DOI: https://doi.org/10.6023/cjoc202008042

Recent Progress in the Synthesis of N-Substituted-1,2,3-triazoles

  • Liu Qishun ,
  • Lü Yufen ,
  • Bao Pengli ,
  • Yue Huilan ,
  • Wei Wei
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  • a School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu, Shandong 273165;
    b Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining 810008

Received date: 2020-08-24

  Revised date: 2020-09-28

  Online published: 2020-10-15

Supported by

Project supported by the Youth Innovation and Technology Project of Shandong Province (No. 2019KJC021), the Natural Science Foundation of Shandong Province (No. ZR2018MB009) and the International Cooperation Project of Qinghai Province (No. 2018-HZ-806).

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Abstract

N-Substituted-1,2,3-triazoles are an important class of nitrogen-containing hetrocyclic compounds, which exhibited wide applications in various fields such as medicinal chemistry, synthetic chemistry and materials. Therefore, their synthetic methods have attracted great attention of chemists. Herein, the recent research progress in the synthesis of N-substituted-1,2,3-triazoles is summarized. The synthetic routes and reaction mechanisms from raw materials such as azide compounds, diazo compounds, TsNHNH2, hydrazones and NH-1,2,3-triazoles are introduced and reviewed, respectively. Finally, the future development of this field is also prospected.

Key words： N-substituted-1,2,3-triazole; azide compound; hydrazone; TsNHNH2; diazo compound; NH-1,2,3-triazole

Cite this article

Liu Qishun , Lü Yufen , Bao Pengli , Yue Huilan , Wei Wei . Recent Progress in the Synthesis of N-Substituted-1,2,3-triazoles[J]. Chinese Journal of Organic Chemistry, 2020 , 40(12) : 4015 -4030 . DOI: 10.6023/cjoc202008042

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