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Chinese Journal of Organic Chemistry >

2021 , Vol. 41 >Issue 4: 1734 - 1738

DOI: https://doi.org/10.6023/cjoc202010014

NOTES

Synthesis of Nitro-Functionalized Isoquinolinediones via NaNO2/Na2S2O8-Mediated Arylnitration of Alkenes

  • Lingling Zhang ,
  • Zhi Wang ,
  • Jian Wu ,
  • Xiaoqing Li
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  • a Jiangsu Academy of Environmental Industry and Technology Corp., Nanjing 210019
    b College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014
* Corresponding authors. E-mail: ;
E-mail:

Received date: 2020-10-11

  Revised date: 2020-11-13

  Online published: 2020-12-05

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Abstract

A new method for the synthesis of nitro-functionalized isoquinolinediones by arylnitration of methacryloylbenzamides has been reported. Readily accessible NaNO2/Na2S2O8 was used as nitro radical precursor, and 18-crown-6 was used to promote the reaction. Compared with the existing method, this method is not only environmentally friendly but also easy to operate.

Key words： Keywords alkenes; arylnitration; cyclization; nitro radical; isoquinolinediones

Cite this article

Lingling Zhang , Zhi Wang , Jian Wu , Xiaoqing Li . Synthesis of Nitro-Functionalized Isoquinolinediones via NaNO2/Na2S2O8-Mediated Arylnitration of Alkenes[J]. Chinese Journal of Organic Chemistry, 2021 , 41(4) : 1734 -1738 . DOI: 10.6023/cjoc202010014

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