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Chinese Journal of Organic Chemistry >

2021 , Vol. 41 >Issue 6: 2417 - 2423

DOI: https://doi.org/10.6023/cjoc202011037

ARTICLES

A Long-Wavelength Fluorescent Probe for Naked Eye Recognition of HSO3-/SO32- in Aqueous Solution and Its Application

  • Chao Wang ,
  • Xin Wang ,
  • Keli Zhong ,
  • Shuhua Hou ,
  • Xiaomei Yan ,
  • Yanjiang Bian ,
  • Lijun Tang
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  • a College of Chemistry and Material Engineering, Bohai University, Jinzhou, Liaoning 121013
    b College of Laboratory Medicine, Dalian Medical University, Dalian, Liaoning 116044
*Corresponding authors.E-mail:;

Received date: 2020-11-30

  Revised date: 2021-01-17

  Online published: 2021-02-26

Supported by

National Natural Science Foundation of China(21878023); National Natural Science Foundation of China(U1608222); and the Program for Distinguished Professor of Liaoning Province.

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Abstract

3-Cyano-4-(3-formyl-4-hydroxystyryl)-5,5-dimethylfuran-2(5H)-alkylene)malononitrile derivative CDM was synthesized. The correctness of its structure was verified by 1H NMR, 13C NMR and HRMS. CDM can recognize HSO3-/SO32- with the naked eye through the fluorescent signal “ON-OFF” in MeCN/Tris ( V∶V=2∶8, pH=7.4) solution, and the color changes from pink to colorless. The probe CDM has good anti-interference ability and fast response speed (200 s), the pH applicable range is 7~14, and the detection limits of the fluorescence and UV absorption spectrum are 6.07 and 1.59 μmol/L. The experimental research shows that CDM can detect HSO3-/SO32- in real water samples and sugar samples and, can perform fluorescent image HSO3-/SO32- in living cells.

Key words： fluorescent probe; HSO3-/SO32-; long wavelength; naked eye recognition; cell imaging

Cite this article

Chao Wang , Xin Wang , Keli Zhong , Shuhua Hou , Xiaomei Yan , Yanjiang Bian , Lijun Tang . A Long-Wavelength Fluorescent Probe for Naked Eye Recognition of HSO3-/SO32- in Aqueous Solution and Its Application[J]. Chinese Journal of Organic Chemistry, 2021 , 41(6) : 2417 -2423 . DOI: 10.6023/cjoc202011037

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