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Chinese Journal of Organic Chemistry >

2021 , Vol. 41 >Issue 7: 2810 - 2819

DOI: https://doi.org/10.6023/cjoc202102037

ARTICLES

Synthesis of 2-Imino-1,2-dihydroquinolines via Copper Catalysis

  • Gaige Zhu ,
  • Xiaohui Lai ,
  • Siyu Wang ,
  • Caixia Lin ,
  • Yaofeng Yuan
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  • College of Chemistry, Fuzhou University, Fuzhou 350108
* Corresponding authors. E-mail: ;

Received date: 2021-02-21

  Revised date: 2021-03-23

  Online published: 2021-04-12

Supported by

National Natural Science Foundation of China(21772023); National Natural Science Foundation of China(22071025)

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Abstract

A mild three-component method for the synthesis of 2-imino-1,2-dihydroquinoline compounds has been successfully developed. In the presence of CuCl, various terminal alkynes, sulfonyl azides and 2-aminobenzaldehydes were coupled. When changing the type of substrate alkyne, controlled synthesis of dihydroquinoline and sulfonyl amidine compounds were achieved.

Key words： 2-imino-1; 2-dihydroquinoline; three-component synthesis; sulfonyl azides; alkynes

Cite this article

Gaige Zhu , Xiaohui Lai , Siyu Wang , Caixia Lin , Yaofeng Yuan . Synthesis of 2-Imino-1,2-dihydroquinolines via Copper Catalysis[J]. Chinese Journal of Organic Chemistry, 2021 , 41(7) : 2810 -2819 . DOI: 10.6023/cjoc202102037

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