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Chinese Journal of Organic Chemistry >

2021 , Vol. 41 >Issue 7: 2898 - 2904

DOI: https://doi.org/10.6023/cjoc202102029

Sesquiterpene Lactones fromDendranthema vestitum(Hemsl.) Ling

  • Wenqi Liu ,
  • Jiayi She ,
  • Ying Yang ,
  • Shiming Zhu ,
  • Xiaoqin Xiong ,
  • Fen Tan ,
  • Hongquan Zhang ,
  • Xinzhou Yang ,
  • Guoping Zeng
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  • a Department of Chemistry and Life Science, Hubei University of Education, Wuhan 430205
    b Hubei Key Laboratory of Purification and Application of Plant Anti-cancer Active Ingredients, Wuhan 430205
    c College of Pharmacy, South-Central University for Nationalities, Wuhan 430074
* Corresponding authors. E-mail: ;
;

Received date: 2021-02-17

  Revised date: 2021-03-26

  Online published: 2021-04-25

Supported by

National Natural Science Foundation of China(21602052); National Natural Science Foundation of China(81903115); Science Research Project of Hubei Provincial Department of Education(B2019178); Undergraduate Innovation and Entreoreneurship Training Progam of Hubei Province(S202014099006)

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Abstract

The chemical constituents fromDendranthema vestitum(Hemsl.) Ling were isolated and purified by solvent extraction, Diaion HP-20, Sephadex LH-20, silica gel and preparative high performance liquid chromatography. Their structures were elucidated based on their spectroscopic data. Four new compounds which belong to guaianolide, named as (1S,5R,6S, 7S,10S)-2-oxo-guaia-3,11(13)-dien-12,6-olide (1), (1S,5R,6R,7R,8S,10S)-2-oxo-8-isobutyryloxy-guaia-3,11(13)-dien-12,6-oli- de (2), (1S,5R,6R,7R,8S,10S)-2-oxo-8-(2'-methyl)butyryloxy-guaia-3,11(13)-dien-12,6-olide (3) and (1R,5R,6R,7R,8S,10S, 11S)-2-oxo-8-acetoxy-guaia-3-en-12,6-olide (4) together with two known compounds matricarin (5) and 11,13-dehydromatricarin (6) were isolated from chloroform extract ofDendranthema vestitum(Hemsl.) Ling.

Key words： Dendranthema vestitum(Hemsl.) Ling; sesquiterpene lactones; guaianolide

Cite this article

Wenqi Liu , Jiayi She , Ying Yang , Shiming Zhu , Xiaoqin Xiong , Fen Tan , Hongquan Zhang , Xinzhou Yang , Guoping Zeng . Sesquiterpene Lactones fromDendranthema vestitum(Hemsl.) Ling[J]. Chinese Journal of Organic Chemistry, 2021 , 41(7) : 2898 -2904 . DOI: 10.6023/cjoc202102029

References

[1]
(Editorial Committee of Flora of China, Flora of China, Vol. 76 Science Press, Beijing. 1983, p. 30 (in Chinese).
[1]
(中国科学院中国植物志编辑委员会, 中国植物志.第76卷 科学出版社, 北京. 1983, p. 30.)
[2]
Zi,X. Z.; Zhang,D. C. Da Bie Shan Sylva. China Forestry Publishing House, Beijing. 2006, p.1110 (in Chinese).
[2]
( 訾兴中, 张定成, 大别山植物志. 中国林业出版社, 北京, 2006, p. 1110.)
[3]
Wang,G. L.; Zhu,X. Q.; Yuan, P.; Yuan,Y. M. J. Wuhan Bot. Res. 1995, 13,383 (in Chinese).
[3]
( 王国亮, 朱信强, 袁萍, 袁焱明, 武汉植物学研究, 1995, 13,383.)
[4]
Wang,G. L.; Wang,J. F.; Jia,W. J.; Zhu,X. Q.; Yuan,Y. M. J. Wuhan Bot. Res. 1988, 6,139 (in Chinese).
[4]
( 王国亮, 王金凤, 贾卫疆, 袁焱明, 武汉植物学研究, 1988, 6,139.)
[5]
Hou,C. C.; Lin,S. J.; Cheng,J. T.; Hsu,F. L. J. Nat. Prod. 2003, 66,625.
[6]
Nishimura, K.; Miyase, T.; Ueno, A.; Noro, T.; Kuroyanagi, M.; Fukushima, S. Phytochemistry 1986, 25,2375.
[7]
Herz, D.; Santhanam,P. S. J. Org. Chem. 1965, 30,4340.
[8]
Hao,X. C.; Zhang,J. W.; Zhan,G. Q.; Xue,Y. B.; Luo,Z. W.; Yao,G. M.; Zhang,Y. H. Biochem. Syst. Ecol. 2013, 51,78.
[9]
Ahmed,A. A.; Gáti, T.; Hussein,T. A.; Ali,A. T.; Tzakou,O. A.; Couladis,M. A.; Mabry,T. J.; Tóth, G. Tetrahedron 2003, 59,3729.
[10]
Mariano,M. V.; Alejandra,M. Z.; Pedro,J. N. J. Nat. Prod. 1988, 51,221.
[11]
Zhang, J.; Kong,L. Y. Chin. Pharm. J. 2005, 40,1778 (in Chinese).
[11]
( 张健, 孔令义, 中国药学杂志, 2005, 40,1778.)
[12]
Lee,S. H.; Kang,H. M.; Song,H. C.; Lee, H.; Lee,U. C.; Son,K. H.; Kim,S. H.; Kwon,B. M. Tetrahedron 2000, 56,4711.
[13]
Dolomanov,O. V.; Bourhis,L. J.; Gildea,R. J.; Howard,J. A.K.; Puschmann, H. J. Appl. Cryst. 2009, 42,339.
[14]
Sheldrick,G. M. Acta Crystallogr., ect. A 2015, 71,3.
[15]
Sheldrick,G. M. Acta Crystallogr., ect. C 2015, 71,3.
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