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Chinese Journal of Organic Chemistry >

2023 , Vol. 43 >Issue 1: 74 - 93

DOI: https://doi.org/10.6023/cjoc202207022

Research and Application of N-Ts Cyanamides in Organic Synthesis

  • Chuanchuan Wang ,
  • Zhiwei Ma ,
  • Xuehui Hou ,
  • Longhua Yang ,
  • Yajing Chen
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  • a Faculty of Science, Henan University of Animal Husbandry and Economy, Zhengzhou 450046
    b School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001
† These authors contributed equally to this work.
* Corresponding authors. E-mail: ;

Received date: 2022-07-13

  Revised date: 2022-08-08

  Online published: 2022-09-15

Supported by

Natural Science Foundation of Henan Province(212300410152); Henan University of Animal Husbandry and Economy(2019HNUAHEDF011); Henan University of Animal Husbandry and Economy(XKYCXJJ2020006)

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Abstract

N-Ts cyanamide, which has been widely used in the construction of nitrogen-containing framework, is one of the efficient and practical multifunctional synthetic precursors in organic synthesis. The progress in application of N-Ts cyanamide according to the reaction types is summarized, including the application in cyanation, cyclization reaction via cyanamide anion, cyanamidation, sulfonylation and cyclization reaction via cyano-group. The future development direction of this field is also prospected.

Key words： N-Ts cyanamides; cyanation; cyanamidation; sulfonylation; cyclization reactions

Cite this article

Chuanchuan Wang , Zhiwei Ma , Xuehui Hou , Longhua Yang , Yajing Chen . Research and Application of N-Ts Cyanamides in Organic Synthesis[J]. Chinese Journal of Organic Chemistry, 2023 , 43(1) : 74 -93 . DOI: 10.6023/cjoc202207022

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