Chinese Journal of Organic Chemistry >
O2-Enabled C—H Imination of Five-Membered Cyclic Enamines
Received date: 2022-12-19
Revised date: 2023-01-22
Online published: 2023-03-17
Supported by
Quality Engineering Project of Anhui Provincial Education Department(2020kfkc362); Platform Project of Chuzhou City Vocation College(2023zkzd05)
An O2-enabled C—H imination of five-membered cyclic enamines is reported. Metal-free catalytic three- component reactions of tetronic acid- or 1,3-cyclopentanedione-derived enaminones with arylglyoxals and arylamines worked well under microwave irradiation, furnishing a series of α-enamino-α-aroyl imines with good yields and complete stereoselectivity. In this reaction process, air serves as the green oxidant with water as the sole byproduct.
Key words： three component; regioselective imination
Wei Fan . O2-Enabled C—H Imination of Five-Membered Cyclic Enamines[J]. Chinese Journal of Organic Chemistry, 2023 , 43(7) : 2492 -2498 . DOI: 10.6023/cjoc202212025
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