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Chinese Journal of Organic Chemistry >

2023 , Vol. 43 >Issue 8: 2968 - 2972

DOI: https://doi.org/10.6023/cjoc202212010

Lignanolides with Antioxidant Activity from the Stems of Dracaena angustifolia

  • Ting Zhao ,
  • Xuhua Nong ,
  • Jiali Wang ,
  • Kuanyu Xu ,
  • Minmin Tang ,
  • Jiling Yi ,
  • Changri Han ,
  • Guangying Chen
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  • a Key Laboratory of Tropical Medicinal Plant Chemistry of Hainan Province, College of Chemistry and Chemical Enginneeering, Hainan Normal University, Haikou 571158
    b Key Laboratory of Tropical Medicinal Resource Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158
    c Coconut Research Institute of Chinese Academy of Tropical Agricultural Sciences, Wenchang, Hainan 571339
    d Key Laboratory of Medicinal and Edible Plants Resources of Hainan Province, Hainan Vocational |University of Science and Technology, Haikou 571126
†The authors contributed equally to this work
*E-mail:

Received date: 2022-12-08

  Revised date: 2023-03-17

  Online published: 2023-04-10

Supported by

The National Natural Science Foundation of China(41866005); The National Natural Science Foundation of China(41606100); The Key Science and Technology Program of Hainan Province(ZDKJ202008); The Innovation Platform for Academicians of Hainan Province(YSPTZX202030); The Hainan Provincial Natural Science Foundation(221RC1054)

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Abstract

A new lignanolide given a trivial name angudracanolide A (1), together with three known lignans 2~4 and three known phenylpropanoids 5~7, was isolated from the stems of Dracaena angustifolia. The complete structure of new compound was elucidated by analysis of spectroscopic data and quantum chemistry calculations. Compounds 1~4 showed obvious antioxidant activity with IC50 values of 15, 19, 25, 30 mmol/L, respectively by comparing the standard trolox with a IC50 value of 45 mmol/L.

Key words： Dracaena angustifolia; lignan; antioxidant activity

Cite this article

Ting Zhao , Xuhua Nong , Jiali Wang , Kuanyu Xu , Minmin Tang , Jiling Yi , Changri Han , Guangying Chen . Lignanolides with Antioxidant Activity from the Stems of Dracaena angustifolia[J]. Chinese Journal of Organic Chemistry, 2023 , 43(8) : 2968 -2972 . DOI: 10.6023/cjoc202212010

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