Chinese Journal of Organic Chemistry >
Research Progress in the Synthesis of Polymethine Chain Modified Cyanine Dyes
Received date: 2023-04-16
Revised date: 2023-05-25
Online published: 2023-06-07
Supported by
The National Natural Science Foundation of China(21807086); The Natural Science Basic Research Program of Shaanxi Province(2022JM-096); The Natural Science Foundation of Shaanxi Provincial Department of Education(12JK0639); The Xi'an University of Architecture and Technology “Great Innovation Plan” Project in 2022(X2022159)
Among small molecule fluorescent probes, cyanine dyes have been widely used in imaging and biosensing fields due to their good optical properties. Functionalization of the polymethine chain, which can significantly improve the stability of dyes and alter their photophysical properties and biological selectivity, has become a hotspot for structural modification of cyanine dyes in recent years. The synthesis methods of polymethine chain modified cyanine dyes are summarized and the progress of polymethine chain modified cyanine dyes is reviewed according to different lengths of polymethine chain, based on different sources of polymethine chain substituents.
Key words： cyanine dyes; polymethine chain modification; synthetic methods
Li Guan , Yanyan Zhou , Yongbao Mao , Kaisen Fu , Wenhui Guan , Yile Fu . Research Progress in the Synthesis of Polymethine Chain Modified Cyanine Dyes[J]. Chinese Journal of Organic Chemistry, 2023 , 43(8) : 2682 -2698 . DOI: 10.6023/cjoc202304019
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