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Chinese Journal of Organic Chemistry >

2024 , Vol. 44 >Issue 11: 3531 - 3540

DOI: https://doi.org/10.6023/cjoc202403050

NOTE

Cu(OTf)2 Catalyzed Rapid Nucleophilic Substitution of Propargyl Alcohols

  • Shunji Zhang ,
  • Huili Liu ,
  • Yun Jin
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  • College of Chemistry and Materials Science, Huaibei Normal University, Huaibei, Anhui 235000
*Corresponding author. E-mail:

Received date: 2024-03-29

  Revised date: 2024-05-15

  Online published: 2024-06-24

Supported by

Natural Science Research Project of Anhui Educational Committee(2022AH050409)

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Abstract

The propargylation of various nucleophiles including indoles, phenol, anisole, enoxysilanes, and alcohols was rapidly achieved using catalytic copper(II) triflate. The reaction conditions are mild, allowing for quick reactions in an undried solvent and under atmospheric air. The desired products are obtained with good yields.

Key words： Cu(OTf)2; catalysis; propargyl alcohol; velocity; nucleophilic substitution

Cite this article

Shunji Zhang , Huili Liu , Yun Jin . Cu(OTf)2 Catalyzed Rapid Nucleophilic Substitution of Propargyl Alcohols[J]. Chinese Journal of Organic Chemistry, 2024 , 44(11) : 3531 -3540 . DOI: 10.6023/cjoc202403050

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