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Chinese Journal of Organic Chemistry >

2025 , Vol. 45 >Issue 3: 814 - 836

DOI: https://doi.org/10.6023/cjoc202409039

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Advances in the Total Synthesis of Ganoderma Meroterpenoids

  • Zhiyu Gao ,
  • Xuena Lu ,
  • Yiqing Li ,
  • Li Ren ,
  • Hongdong Hao
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  • Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F University, Yangling, Shaanxi 712100
* E-mail: ;

Received date: 2024-09-27

  Revised date: 2024-12-17

  Online published: 2024-12-27

Supported by

Natural Science Research Program of Shaanxi Province(2024JC-YBMS-641); National Natural Science Foundation of China(21901211); National Natural Science Foundation of China(81903466); National Natural Science Foundation of China(22471221)

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Abstract

Ganoderma meroterpenoids are natural products containing aromatic ring with terpenoid fragments. In recent years, numerous Ganoderma meroterpenoids with novel carbon skeleton and different oxidation state were discovered by Chinese scientists. Among these natural product, anti-renal fibrosis, anti-inflammatory, anti-Alzheimer’s disease, antioxidant, hypoglycemic activities and calcium channel inhibitory were reported. Therefore, these natural products have attracted attention from pharmacology and synthetic chemists. The progress on the total synthesis of Ganoderma meroterpenoids is summarized.

Key words： Ganoderma; meroterpenoids; total synthesis

Cite this article

Zhiyu Gao , Xuena Lu , Yiqing Li , Li Ren , Hongdong Hao . Advances in the Total Synthesis of Ganoderma Meroterpenoids[J]. Chinese Journal of Organic Chemistry, 2025 , 45(3) : 814 -836 . DOI: 10.6023/cjoc202409039

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