Chinese Journal of Organic Chemistry >
Recent Progress in the Total Synthesis of Daphniphyllum Alkaloids
Received date: 2024-09-16
Revised date: 2024-10-31
Online published: 2024-12-19
Supported by
National Natural Science Foundation of China(22271136); National Natural Science Foundation of China(22471117); Shenzhen Science, Technology and Innovation Commission(JCYJ20220814203252001); Shenzhen Key Laboratory of Small Molecule Drug Discovery and Synthesis(ZDSYS20190902093215877); Guangdong Provincial Key Laboratory of Catalysis(2020B121201002); Guangdong Innovative Program(2019BT02Y335); Education Department of Guangdong Province, Key Research Projects in Colleges and Universities in Guangdong Province(2021ZDZX2035); Innovative Team of Universities in Guangdong Province(2020KCXTD016)
Since the isolation of the first member in 1909, over 300 Daphniphyllum alkaloids have been isolated to date. These Daphniphyllum alkaloids have attracted the attention of many organic chemists due to their wide range of biological activities and complex, diverse and polycyclic skeletal structures. So far, more than 40 Daphniphyllum alkaloids have been synthesized. In this review, the research works of different research groups on the total synthesis of 27 Daphniphyllum alkaloids since 2021 are summarized.
Haikang Mao , Jing Xu . Recent Progress in the Total Synthesis of Daphniphyllum Alkaloids[J]. Chinese Journal of Organic Chemistry, 2025 , 45(3) : 866 -880 . DOI: 10.6023/cjoc202409017
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