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DOI: https://doi.org/10.6023/cjoc202506036

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Fundamentals of electron upconversion and its applications in organocatalysis

  • Zhu Wenhui ,
  • Yang Jin-Dong
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  • Center of Basic Molecular Science, Department of Chemistry, Tsinghua University, Beijing, 100084

Received date: 2025-06-30

  Revised date: 2025-07-31

  Online published: 2025-08-27

Supported by

National Natural Science Foundation of China (No. 22222106, 22193011, and 22393891).

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Abstract

Photon upconversion, an anti-Stokes process that elevates photon energy, has become indispensable in photonic materials and optoelectronic devices. Inspired by this physical phenomenon, chemists have recently transposed its fundamental concept to organic catalysis, establishing electron upconversion as an innovative catalytic paradigm. The thermodynamic and kinetic advantages of electron upconversion originate from two key features: (1) radical transformations exhibit significantly reduced energy release and accelerated reaction rates compared to ground-state processes; (2) the upconverted intermediates complete catalytic cycles via facile electron transfer mechanisms. Three principal electron upconversion strategies have been developed: molecular dissociation (e.g., homolytic bond cleavage), molecular association (e.g., three-electron bond formation), and super-electron-donor systems. These groundbreaking approaches have demonstrated remarkable efficacy in pivotal organic transformations including C-N cross-coupling and Si-Si bond activation, opening new avenues for sustainable catalysis development. This article provides a comprehensive discussion of the theoretical mechanisms (including thermodynamic and kinetic fundamentals), reaction types, and applications in catalytic synthesis, while also summarizing cutting-edge developments in related fields.

Key words： electron upconversion; dissociation; association; super-electron-donors; reductants

Cite this article

Zhu Wenhui , Yang Jin-Dong . Fundamentals of electron upconversion and its applications in organocatalysis[J]. Chinese Journal of Organic Chemistry, 0 : 13 -13 . DOI: 10.6023/cjoc202506036

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