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0 202506024 - 202506024

DOI: https://doi.org/10.6023/cjoc202506024

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Efficient Hydrogenation of Ketones to Alcohols Catalysed by Phosphinoamine Rhenium Complexes

  • Fang Xiaolong ,
  • Wang Jun ,
  • Xu Shuting ,
  • Li Hao ,
  • Hu Kun ,
  • Chen Yiyu
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  • aKey Laboratory of Functional Molecule Design and Interface Process, Anhui Jianzhu University, Hefei 230601;
    bSchool of Architecture and Urban Planning, Anhui Jianzhu University, Hefei 230601

Received date: 2025-06-18

  Revised date: 2025-07-22

  Online published: 2025-09-04

Supported by

Natural Science Foundation of China (No. 21802010, 22401003), the Natural Science Foundation of Anhui Province (No. 2308085MB49), and the Fund for Outstanding Young Scholars of Anhui Province (No. 2023AH030038).

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Abstract

Rhenium complexes (Ph2PCH2CH2NH2)Re(CO)3Cl (1), (Ph2PCH2CH2CH2NH2)Re(CO)3Cl (2), (o-Ph2PC6H4NH2)Re(CO)3Cl (3), [(Ph2PCH2CH2NH2)2Re(CO)2]Cl (4), [(Ph2PCH2CH2CH2NH2)2Re(CO)2]Cl (5), and [(o-Ph2PC6H4NH2)2Re(CO)2]Cl (6), were applied for the first time in homogeneous catalytic hydrogenation of ketones to alcohols. Complexes with one PN ligand (1-3) and two PN ligands (4-6) exhibited comparable catalytic performance. Using optimal complex 2, the important factors with significant influences on the catalytic activity were well optimized, including the loading of catalyst, additive, temperature, and so on. Under suitable conditions, complex 2 effectively hydrogenated nearly 30 diverse ketones to their corresponding alcohols.

Key words： rhenium complex; bidentate PN ligand; catalytic hydrogenation; ketone

Cite this article

Fang Xiaolong , Wang Jun , Xu Shuting , Li Hao , Hu Kun , Chen Yiyu . Efficient Hydrogenation of Ketones to Alcohols Catalysed by Phosphinoamine Rhenium Complexes[J]. Chinese Journal of Organic Chemistry, 0 : 202506024 -202506024 . DOI: 10.6023/cjoc202506024

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