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DOI: https://doi.org/10.6023/cjoc202601037

ARTICLE

The Photochemical C-H Oxidation of Alkylarenes to Aldehydes and Ketones by an Organic Photocatalyst

  • Li Wenjing ,
  • Liu Chunye ,
  • Liang Lingling ,
  • Miao Yanqing ,
  • You Jing ,
  • Shen Siyu
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  • School of pharmacy, Xi'an Medical University, Xi'an, 710021

Received date: 2026-03-20

  Revised date: 2026-04-08

  Online published: 2026-06-04

Supported by

Foundation of Shaanxi Province Science and Technology Department of China (Nos. 2025JC-YBQN-136, 2025JC-YBMS-178), the Shaanxi Provincial Department of Education (No. 24JK0646) and Xi'an Medical University (Nos. 2023BS30).

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Abstract

Photooxygenation of benzylic C(sp3)-H by oxygen occurs efficiently under photoirradiation of Eosin Y to yield aldehydes and ketones, which is able to activate alkylarenes such as toluene and can overcome the overoxidation into carboxylic acids. This approach features cheap photocatalyst, broad substrate scope, easy scale up and further transformation. In addition, the photophysical characteristics of the Eosin Y and the reaction mechanism were also discussed.

Key words： photochemical; Eosin Y; benzylic C(sp3)-H; aldehydes and ketones

Cite this article

Li Wenjing , Liu Chunye , Liang Lingling , Miao Yanqing , You Jing , Shen Siyu . The Photochemical C-H Oxidation of Alkylarenes to Aldehydes and Ketones by an Organic Photocatalyst[J]. Chinese Journal of Organic Chemistry, 0 : 0 . DOI: 10.6023/cjoc202601037

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