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Chinese Journal of Organic Chemistry >

2026 202604044

DOI: https://doi.org/10.6023/cjoc202604044

ARTICLE

Efficient Transfer Hydrogenation of Ketones and Aldehydes to Alcohols Catalysed by PNP-Rhenium Complexes

  • Duan Shuopeng ,
  • Feng Shangsong ,
  • Li Junxiao ,
  • Hu Kun ,
  • Li Hao ,
  • Fang Xiaolong
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  • aKey Laboratory of Functional Molecule Design and Interface Process, Anhui Jianzhu University, Hefei 230601;
    bAnhui Lvheng Environmental Protection Technology Co. Ltd., Wuhu 241007
†These authors contributed equally to this work.

Received date: 2026-06-01

  Revised date: 2026-08-03

  Online published: 2026-09-08

Supported by

Natural Science Foundation of China (No. 21802010, 22401003), the Natural Science Foundation of Anhui Province (No. 2308085MB49), the Fund for Outstanding Young Scholars of Anhui Province (No. 2023AH030038), the Scientific Research Startup Foundation of Anhui Jianzhu University (No. 2023QDZ28), and the Quality Engineering Foundation of Anhui Jianzhu University (No. 2023jy71).

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Abstract

Rhenium(I)-NH complexes featuring bidentate PN, tridentate PNP, and tetradentate PNNP ligands were employed as catalysts for the transfer hydrogenation of ketones and aldehydes to alcohols. The structure of the phosphinoamine ligand significantly influenced the transfer hydrogenation performance of the resulting complexes, among which complex HN(CH2CH2PPh2)2Re(CO)2Cl (7) exhibited the highest activity. Following optimization of key factors including catalyst loading, additive, and temperature, activity tests demonstrated that 7 could efficiently catalyze the transfer hydrogenation of nearly 50 diverse ketones and aldehydes to their corresponding alcohols. Under suitable conditions, complex 7 also enabled the chemoselective hydrogenation of unsaturated aldehydes to afford unsaturated alcohols in high efficiency.

Key words： rhenium complex; phosphinoamine ligand; transfer hydrogenation; ketone; aldehyde

Cite this article

Duan Shuopeng , Feng Shangsong , Li Junxiao , Hu Kun , Li Hao , Fang Xiaolong . Efficient Transfer Hydrogenation of Ketones and Aldehydes to Alcohols Catalysed by PNP-Rhenium Complexes[J]. Chinese Journal of Organic Chemistry, 2026 : 202604044 . DOI: 10.6023/cjoc202604044

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