化学学报 ›› 1956, Vol. 22 ›› Issue (5): 352-355. 上一篇    下一篇

论文

用铁粉和氯化铵还原芳香族硝基化合物

石毓澊   

  1. 北京医学院药学系
  • 收稿日期:1956-06-09 出版日期:1956-10-15 发布日期:2013-06-04

THE REDUCTION OF AROMATIC NITRO COMPOUNDS WITH IRON FILINGS IN THE PRESENCE OF AMMONIUM CHLORIDE

SHIH YU-TSUN   

  1. Department of Pharmacy, Peking Medical College
  • Received:1956-06-09 Online:1956-10-15 Published:2013-06-04

用氯化铵与铁粉还原具有羧基(及其酯类)、磺醯氨基、腈基及其他取代基的硝基化合物,一般产率都在80%以上。对於具有水解可能的取代基的硝基化合物,在还原时也未发现水解现象;只是还原具有羧基的硝基化合物时不懂产率较低,而且在还原时还发生反应物变稠现象,致使搅拌及过滤都感到很大困难。适当地调节还原剂的pH值,就可以避免这种变稠现象。

Aromatic ammo compounds containing carboxyl,carbethoxyl,cyano,different groups were prepared from the corresponding nitro compounds sulfamido and other by means of reduction with iron filings in the presence of ammonium chloride.yields were generally over 80%.During the reduction of the aromatic nitro compounds possessing different functional groups,there obtained iron sludges of different compositions,colours and degrees of fineness.The sludges from the easily reduced nitro compounds contained less ferrous oxide than those from the difficultly reduced ones.