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化学学报
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化学学报 ›› 1981, Vol. 39 ›› Issue (2): 153-158. 上一篇    下一篇

论文

紫金牛抗结核成分的化学结构

胡燕1, 陈文森1, 黄步汉1, 林隆泽2, 徐任生2   

  1. 1. 中国科学院华南植物研究所 广州;
    2. 中国科学院上海药物研究所
  • 投稿日期:1979-03-23 发布日期:2013-06-03

STRUCTURE OF ANTITUBERCULAR COMPOUNDS FROM ARDISIA JAPONICA (Thunb.) BIUME

Hu YAN1, CHEN WEN-SEN1, HUANG BU-HAN1, LIN LONG-ZE2, XU REN-SHENG2   

  1. 1. South China Institute of Botany, Academia Sinica, Guanzhou;
    2. Shanghai Institute of Materia Medica, Academia Sinica
  • Received:1979-03-23 Published:2013-06-03

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被引次数

14

从民间抗结核草药紫金牛全草中分得两个新的间苯二酚烯基衍生物,紫金牛酚Ⅰ(1)和紫金牛酚Ⅱ(2)。体外抑制结核菌试验表明,它们为该植物抑制结核杆菌生长的有效成分,经光谱分析与化学降解方法证明,1为2-甲基-5-[8'(顺)-十三烯基]-间苯二酚,2为5-[8'(顺)-十三烯基]-间苯二酚。

The Chinese medicinal herb,Ardisia japonica (Thunb.) Blume (Myrsinaceae),has been used for treatment of tuberculosis and asthma in folk medicine,Two new amorphous resorcinol derivatives,named ardisinol Ⅰ(1) and ardisinol Ⅱ(2),have been isolated from tho active fraction of its alcoholic extract and both are active in the antitubercular tests in vitro.Ardisinol I has a formula of C20H32O2,m.p.36-37℃.