化学学报 ›› 1983, Vol. 41 ›› Issue (8): 723-729. 上一篇    下一篇

研究论文

氟氯代β-二酮的合成

黄维垣;张龙庆;胡昌明   

  1. 中国科学院上海有机化学研究所
  • 发布日期:1983-08-15

Study on synthesis of fluorochloroalkyl β-diketones

HUANG WEIYUAN;ZHANG LONGQING;HU CHANGMING   

  • Published:1983-08-15

关键词: 乙酯, 有机氯化合物, 有机氟化合物, 乙酸 P, β双酮类

Several fluorochlore β-diketones were synthesized from Claisen condensation of ethyl difluorochloroacetate with methyl ketone in the presence of sodium ethoxide. The fluorinated methyl ketones, which were used as one of the reactants in the Claisen condensation, were synthesized by the following methods, namely: the addition of methyl Grignard reagent to ethyl difluorochloroacetate; the addition of bis (m-chlorotetrafluorophenyl) cadmium to acetyl chloride and the hydrolytic decomposition of β-keto ester.

Key words: ETHYL ESTER, ORGANO CHLORIDE COMPOUNDS, ORGANO FLUORINE COMPOUNDS, ACETIC ACID P, BETA DIKETONES

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