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化学学报
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化学学报 ›› 2004, Vol. 62 ›› Issue (19): 1935-1940. 上一篇    下一篇

研究论文

两头尖的化学成分研究(I)

夏忠庭1, 刘大有1, 王晓颖1, 刘科峰1, 张培成2   

  1. 1. 长春中医学院药学院, 长春, 130021;
    2. 中国医学科学院北京药物研究所, 北京, 100050
  • 投稿日期:2003-07-04 修回日期:2004-05-27 发布日期:2014-02-17
  • 通讯作者: 刘大有,E-mail:Jcldy@eyou.com E-mail:Jcldy@eyou.com
  • 基金资助:
    国家科技部1035工程(No.96-901-01-89)和吉林省科技厅(No.20020503-14)资助项目.

Studies on the Chemical Constituents of the Rhizoma of Anemone raddeana Regel

XIA Zhong-Ting1, LIU Da-You1, WANG Xiao-Ying1, LIU Ke-Feng1, ZHANG Pei-Cheng2   

  1. 1. Changchun College of Traditional Chinese Medicine, Changchun 130021;
    2. Institute of Materia Medica, Chinese Acadiemy of Medical Sciences, Beijing 100050
  • Received:2003-07-04 Revised:2004-05-27 Published:2014-02-17

PDF

335

被引次数

62

采用硅胶柱色谱和高效液相色谱等方法,对两头尖的化学成分进行了研究,从中分离得到两个化合物,经化学及IR,ESI-MS,1H NMR,13C NMR,DEPT,HMOC,HMBC,GCOSY,TOCSY等谱学分析鉴定其结构分别为:3-O-α-L-arabinopyranosyl(1 → 3)-α-L-rhamnopyranosyl (1 → 2) [ β-D-glucopyranosyl (1 → 4) ]-α-L-arabinopyranosyl oleanolic acid 28-O-α-L-rhamnopyranosyl (1→4)-β-D-glucopyranosyl(1→6)-β-D-glucopyranoside (1), 3-O-β-D-glucopyranosyl(1→4)-β-D-glucopyranosyl(1→3)-α-L-rhamnopyranosyl(1→2)-α-L-arabinopyranosyl oleanolic acid 28-O-α-L-rhamnopyranosyl(1→4)-β-D-glucopyranosyl(1→6)-β-D-glucopyranoside(2),该两个化合物为新化合物,分别命名为:多被银莲花皂苷16(Raddeanoside 16)和多被银莲花皂苷17(Raddeanoside 17).

关键词: 两头尖, 多被银莲花皂苷16, 多被银莲花皂苷17

Two new triterpenoid saponins,raddeanoside 16 and raddeanoside 17 were isolated from the ethanolic extract of the rhizome of Anemone raddeana Regel. Their structures were elucidated as 3-O-α-L-arabinopyranosyl(1→3)-α-L-rhamnopyranosyl(1→2) [β-D-glucopyranosyl(1→4)]-α-L-arabinopyranosyl oleanolic acid 28-O-α-L-rhamnopyranosyl(1→4)-β-D-glucopyranosyl (1→6)-β-D-glucopyranoside (1) and 3-O-β-D-glucopyranosyl(1→4)-β-D-glucopyranosyl(1→3)-α-L-rhamnopyranosyl(1→2)-α-L-arabinopyranosyl oleanolic acid 28-O-α-L-rhamnopyranosyl(1→4)-β-D-glucopyranosyl(1→6)-β-D-glucopyranoside (2) by 1D and 2D NMR spectroscopic methods, including DEPT, HMQC, HMBC, GCOSY and TOCSY experiments, respectively.

Key words: Anemone raddeana Regel, raddeanoside 16, raddeanoside 17