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化学学报
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化学学报 ›› 2005, Vol. 63 ›› Issue (10): 913-918. 上一篇    下一篇

研究论文

对称四甲基六元瓜环与2-氨基甲基吡啶相互作用的研究

赵云洁1，薛赛凤*1，张云黔1，祝黔江1，陶朱1, 张建新2，魏赞斌3，龙腊生3   

  1. (1贵州大学应用化学研究所 贵阳 550025)
    (2贵州省天然产物重点实验室 贵阳 550002)
    (3厦门大学化学系 厦门 361005)
  • 投稿日期:2004-09-13 修回日期:2005-01-18 发布日期:2010-12-10
  • 通讯作者: 薛赛凤

Study of the Interaction of Disubstituted Cucurbit[6]uril with 2-(Aminomethyl)pyridine

ZHAO Yun-Jie1, XUE Sai-Feng*1, ZHANG Yun-Qian1, ZHU Qian-Jiang1, TAO Zhu1, ZHANG Jian-Xin2, WEI Zhan-Bing3, LONG La-Sheng3   

  1. (1 Institute of Applied Chemistry, Guizhou University, Guiyang 550025)
    (2 Key Laboratory of Chemistry for Natural Products of Guizhou Province, Guiyang 550002)
    (3 Department of Chemistry, Xiamen University, Xiamen 361005)
  • Received:2004-09-13 Revised:2005-01-18 Published:2010-12-10
  • Contact: XUE Sai-Feng

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1083

被引次数

38 | 1

分别用核磁共振、紫外可见吸收和X射线单晶衍射方法研究对称四甲基六元瓜环与2-氨基甲基吡啶的相互作用及其结构特征. 1H NMR谱图和紫外可见吸收光谱图清晰表明, 2-氨基甲基吡啶与对称四甲基六元瓜环有明显的相互作用, 客体2-氨基甲基吡啶的吡啶环部分进入了瓜环空腔, 1H NMR谱图相关质子峰的积分强度以及客体吸光度随主体瓜环浓度变化明确表示它们之间形成了1∶1的包结配合物, 此包结比并不随瓜环的浓度增加而改变. X射线单晶衍射法对包结配合物晶体的测定进一步证实了核磁共振、紫外可见吸收方法所得结论.

关键词: 对称四甲基六元瓜环, 2-氨基甲基吡啶, 核磁共振, 紫外可见吸收光谱, X射线单晶衍射, 主客体包结配合物

Interaction and structure of a host-guest inclusion complex of symmetrical tetramethyl substituted cucurbit[6]uril (TMeQ[6]) with 2-(aminomethyl)pyridine (amp) have been studied by using 1H NMR technique, UV-visible spectrophotometry and single crystal X-ray diffraction determination. The experimental results from 1H NMR and UV-visible spectra revealed that the amp as a guest enters into the cavity of TMeQ[6] to form a host-guest inclusion complex of TMeQ[6] and amp with a constant ratio of 1∶1. The single crystal X-ray diffraction determination further confirmed the conclusions.

Key words: symmetrical tetramethylcucurbit[6]uril, 2-(aminomethyl)pyridine, 1H NMR technique, UV-visible spectrophotometry, single crystal X-ray diffraction, host-guest inclusion complex