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化学学报
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化学学报 ›› 2006, Vol. 64 ›› Issue (23): 2384-2388. 上一篇    

研究简报

β-环糊精与N,N'-二(4-吡啶基甲基)-1,6-己二胺自组装包结行为的研究

王志斌, 赵敏, 梁中伟, 陈慧兰*   

  1. (南京大学化学系配位化学重点实验室 南京 210093)
  • 投稿日期:2006-03-21 修回日期:2006-06-21 发布日期:2006-12-14
  • 通讯作者: 陈慧兰

Investigation of the Self-assembled Inclusion Behaviour of β-Cyclodextrin and N,N'-Bis(4-pyridylmethyl)-1,6-hexanediamine

WANG Zhi-Bin; ZHAO Min; LIANG Zhong-Wei; CHEN Hui-Lan*   

  1. (State Key Laboratory of Coordination Chemistry, Department of Chemistry, Nanjing University, Nanjing 210093)
  • Received:2006-03-21 Revised:2006-06-21 Published:2006-12-14
  • Contact: CHEN Hui-Lan

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以4-吡啶甲醛和1,6-己二胺为原料, 合成了含吡啶基的还原双席夫碱客体N,N'-二(4-吡啶基甲基)-1,6-己二胺(C6N4), 通过核磁共振技术研究了β-环糊精与C6N4的自组装包结作用, 测定了包结比和稳定常数. 结果表明, β-环糊精与客体C6N4在水溶液中形成1∶1的包结配合物, 其稳定常数的平均值为1.7×102 dm3•mol－1.

关键词: β-环糊精, 还原双席夫碱, 包结作用, 核磁共振技术

A reduced bis-Schiff base guest containing pyridyl, N,N'-bis(4-pyridylmethyl)-1,6-hexanedi- amine (C6N4), has been synthesized from 4-pyridinecarboxaldehyde and 1,6-hexanediamine. The self-assembled inclusion behaviour of β-cyclodextrin and linear guest C6N4 has been investigated by 1H NMR. Our experimental results revealed that a 1∶1 inclusion complex of β-cyclodextrin and C6N4 could be formed in aqueous solution and the average value of stability constant of inclusion complex was determined to be 1.7×102 dm3•mol－1.

Key words: β-cyclodextrin, reduced bis-Schiff base, inclusion behaviour, NMR technique