化学学报 ›› 1999, Vol. 57 ›› Issue (2): 183-188. 上一篇    下一篇

研究论文

螺环倍半萜(±)-α-花柏烯和(±)-β-花柏烯的全合成

王进军;邱俊;姜贵吉;竹下齐;森章   

  1. 吉林化工学院环境化工系;延边大学化学系;九州大学机能物质科学研究所
  • 发布日期:1999-02-15

Total synthesis of (±)-α-Chamigrene and (±)-β -Chamigrene

Wang Jinjun;Qiu Jun;Jiang Guiji;Zhu Xiaqi;Sen Zhang   

  • Published:1999-02-15

以萜品油烯(terpinolene)与2,4-二氧代戊酸甲酯的deMayo反应得到的加成产物为起始原料,经反-aldol重排,再环合成具有螺[5.5]十一烷结构的基本碳架,通过官能团的化学修饰,完成了(±)-α-花柏烯和(±)-β-花柏烯的全合成。

关键词: 花柏烯, 螺环化合物, 倍半萜

In this paper, (±)-α-Chamigrene and (±)-β-Chamigrene were synthesized via the de Mayo reaction of terpinolene and methyl-2, 4- dioxopentanoate to build up basic skeleton of Chamigrene, which was converted into title products after embellishing the functional groups.

Key words: SPIRO COMPOUNDS, SESQUITERPENE

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