化学学报 ›› 2012, Vol. 70 ›› Issue (08): 1013-1020.DOI: 10.6023/A1109092 上一篇    下一篇

研究论文

基于环糊精二聚体与金刚烷修饰的温敏性聚合物的主客体识别构筑超分子水凝胶

李姝静a, 张小军b, 梁海燕a, 王心蕊a   

  1. a 北京工商大学理学院化学系 北京 100048;
    b 中国农业大学理学院应用化学系 北京 100193
  • 收稿日期:2011-09-09 修回日期:2012-01-05 出版日期:2012-04-28 发布日期:2012-01-05
  • 通讯作者: 李姝静, 张小军
  • 基金资助:

    北京市教育委员会科技发展面上项目(No. KM201210011006).

Supramolecular Hydrogels Obtained by Host-Guest Interactions of Cyclodextrin Dimers with Adamantyl-Containing LCST Copolymers

Li Shujinga, Zhang Xiaojunb, Liang Haiyana, Wang Xinruia   

  1. a Department of Chemistry, School of Science, Beijing Technology and Business University, Beijing 100048;
    b Department of Applied Chemistry, College of Science, China Agricultural University, Beijing 100193
  • Received:2011-09-09 Revised:2012-01-05 Online:2012-04-28 Published:2012-01-05
  • Supported by:

    Supported by Scientific Research Common Program of Beijing Municipal Commission of Education (No. KM201210011006).

利用环糊精二聚体(trans-Stilbene β-CD Dimer)与金刚烷修饰的温敏性聚合物(Pnipam-Ad)的主客体识别作用构筑了超分子水凝胶. 2D NMR 测定结果表明trans-Stilbene β-CD Dimer 和Pnipam-Ad 的主客体相互作用是通过β-CD 空腔和疏水体Ad 形成包结络合物进行的. 环糊精二聚体trans-Stilbene β-CD Dimer 和聚合物Pnipam-Ad 两者之间的缔合程度受trans-Stilbene β-CD Dimer 和Pnipam-Ad 的浓度以及trans-Stilbene β-CD Dimer 光异构的影响. 此外, 由于trans-Stilbene β-CD Dimer 对Pnipam-Ad 聚合物链的物理交联作用使两者混合溶液的最低临界溶解温度(LCST)低于纯聚异丙基丙烯酰胺(Pnipam)的LCST.

关键词: 环糊精二聚体, 主客体相互作用, 温度敏感性, 超分子水凝胶

Supramolecular hydrogels were constructed by the formation of inclusion complexes between trans-Stilbene β-CD Dimer and adamantyl modified poly(N-isopropylacrylamide) (Pnipam-Ad). The results of 2D NMR measurement indicated that the host-guest interaction between trans-Stilbene β-CD Dimer and Pnipam-Ad was carried out through the formation of inclusion complexes between β-CD cavity and the hydrophobe Ad. The interaction between trans-Stilbene β-CD Dimer and Pnipam-Ad was depended on the concentration of trans-Stilbene β-CD Dimer, Pnipam-Ad and the photoisomerization of trans-Stilbene β-CD Dimer. In addition, the lower critical solution temperature (LCST) of the supramolecular networks consisting of trans-Stilbene β-CD Dimer and Pnipam-Ad are significantly lower than those of pure Pnipam.

Key words: cyclodextrin dimer, host-guest interaction, thermo-sensitivity, supramolecular gel