Acta Chimica Sinica ›› 2012, Vol. 70 ›› Issue (05): 635-642 .DOI: 10.6023/A1105271 Previous Articles     Next Articles

Full Papers

淫羊藿炮制前后UPLC-PDA-MS 的指纹图谱研究

朱粉霞a, 赵永刚b, 贾晓斌a, 韦英杰a, 张振海a, 古丽娜尔·吾拉孜汗a   

  1. a 江苏省中医药研究院国家中医药管理局中药释药系统重点研究室 南京 210028;
    b 江苏省环境监测中心 南京 210036
  • 投稿日期:2011-05-27 修回日期:2011-09-05 发布日期:2011-11-22
  • 通讯作者: 贾晓斌
  • 基金资助:

    国家自然科学基金(No. 20973944)资助项目.

Study on Fingerprint of Crude and Processed Epimedium by UPLC-PDA-MS

Zhu Fenxiaa, Zhao Yonggangb, Jia Xiaobina, Wei Yingjiea, Zhang Zhenhaia, Wulazihan Gulinaera   

  1. a Key Laboratory of New Drug Delivery System of Chinese Meteria Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing 210028;
    b Jiangsu Environmental Monitoring Center, Nanjing 210036
  • Received:2011-05-27 Revised:2011-09-05 Published:2011-11-22
  • Supported by:

    Project was supported by the National Natural Science Foundation of China (No. 20973944).

The fingerprint chromatograms of E. koreanum Nakai and E. pubescens Maxim were established by UPLC. The results showed that the fingerprints of two species were significantly different. There were 35 common peaks in crude drug of E. koreanum Nakai in which 26 peaks were identified, and 13 common peaks in crude drug of E. pubescens Maxim in which 9 peaks were identified, by MS respectively. Additionally, there were 5 differences in fingerprint between crude drug and processed product. This method with desirable rapidness, simplity and repeatability can be used for the quality evaluation of crude and processed Epimedium.

Key words: Epimedium, UPLC-PDA-MS, processed, fingerprint