Acta Chimica Sinica ›› 2023, Vol. 81 ›› Issue (7): 836-842.DOI: 10.6023/A23040129 Previous Articles     Next Articles

Review

超声化学在生物医学中应用的研究进展

罗楚文a,b, 孔超颖a,b, 汤朝晖a,b,c,*()   

  1. a 中国科学院长春应用化学研究所 中国科学院生态环境高分子材料重点实验室 长春 130022
    b 中国科学技术大学应用化学与工程学院 合肥 230026
    c 吉林省生物医用高分子材料工程实验室 长春 130022
  • 投稿日期:2023-04-11 发布日期:2023-06-16
  • 作者简介:

    罗楚文, 2022年至今硕士就读于中国科学院长春应用化学研究所, 专业方向为高分子化学与物理.

    孔超颖, 2020年至今博士就读于中国科学院长春应用化学研究所, 材料化学工程专业, 主要从事于超声激活抗肿瘤前药设计的研究.

    汤朝晖, 中国科学院长春应用化学研究所研究员, 博士生导师. 曾在英国帝国理工学院和美国纽约州立大学石溪分校做博士后. 主要从事高分子载体抗肿瘤纳米药物研究. 在Adv. Mater., Adv. Sci., Prog. Polym. Sci., Chem. Sci., Biomateri- als, Nano Lett., J. Control. Release 等知名期刊发表学术论文 120余篇.

    庆祝《化学学报》创刊90周年.
  • 基金资助:
    中国科技部(2022YFE0110200); 国家自然科学基金(52025035)

Research Progress in Sonochemistry for Biomedical Applications

Chuwen Luoa,b, Chaoying Konga,b, Zhaohui Tanga,b,c()   

  1. a Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China
    b School of Applied Chemistry and Engineering, University of Science and Technology of China, Hefei 230026, China
    c Jilin Biomedical Polymers Engineering Laboratory, Changchun 130022, China
  • Received:2023-04-11 Published:2023-06-16
  • Contact: *E-mail: ztang@ciac.ac.cn
  • About author:
    Dedicated to the 90th anniversary of Acta Chimica Sinica.
  • Supported by:
    Ministry of Science and Technology of China(2022YFE0110200); National Natural Science Foundation of China(52025035)

Ultrasound is a kind of mechanical wave, whose frequency exceeds the upper limit of human hearing. Ultrasound has high energy and penetration, which can pierce the barrier of biological soft tissue and induce the occurrence of chemical reactions. In recent years, sonochemistry has been increasingly used in biomedical research, providing a new focus for the development of biomedicine. This review is mainly divided into three parts, the mechanochemistry of ultrasound, the sonochemistry assisted by sonosensitizers, and the cavitation effect of ultrasound, to describe the research progress in sonochemistry for biomedical applications.

Key words: ultrasound, biomedicine, mechanochemistry, sonosensitizer, ultrasonic cavitation