Acta Chimica Sinica ›› 1978, Vol. 36 ›› Issue (3): 199-206. Previous Articles     Next Articles

丹参有效成分的研究——Ⅰ.丹参酮Ⅱ-A磺酸钠和次甲丹参醌的化学结构

钱名堃1, 杨保津1, 顾文华1, 陈政雄1, 陈馨德2, 叶秀琴2   

  1. 1. 中国科学院上海药物研究所;
    2. 上海中药三厂
  • 投稿日期:1977-11-28 发布日期:2013-06-03

STUDIES ON THE ACTIVE PRINCIPLES OF DAN-SHEN——Ⅰ.THE STRUCTURE OF SODIUM TANSHINONE Ⅱ-A SULFONATE AND METHYLENE TANSHINQUINONE

CHIEN MING-KUN1, YOUNG PAO-TSIN1, KU WEN-HUA1, CHEN ZHENG-XIONG1, CHEN HSING-TE2, YEH HSIU-CHIN2   

  1. 1. Shanghai Institute of Materia Medica, Academia Sinica;
    2. Shanghai No.3 Pharmaceutical Factory of Chinese Meteria Medica
  • Received:1977-11-28 Published:2013-06-03

Dan-Shen, the roots of Salvia miltiorrhvsa Bnnge (Labiatae),is a well-known Chines traditional drug used for treatment of various kinds of diseases including coronary disorders. In recent years, indeed the alcoholic extract of this drug was found to be effective to some kinds of coronary diseases after clinical trials. So the above extract was subjected to separation work, and therefrom several known components such as tanshinone Ⅰ, tanshinone Ⅱ-A, tanshinone Ⅱ-B, cryptotanshinone, β-sitosterol,(-)-dihydrotanshinone, methyltanshinonate were isolated. Besides, a new compound was also obtained and named methylenetanshinqninone. Its structure was elucidated as a diterpene qninone (Ⅱ) by chemical methods and spectral analyses.