Acta Chimica Sinica ›› 1999, Vol. 57 ›› Issue (2): 196-201. Previous Articles     Next Articles

Original Articles

O-(3-三苯锗基)正丙基硫代磷酸酯及类似物的合成

曾宪顺;曾强;崔涛;汪清民;李东波   

  1. 南开大学元素有机化学研究所.天津(300071)
  • 发布日期:1999-02-15

Synthesis of O-(3-triphenylgermyl) propyl phosphorothioates and their derivatives

Zeng Xianshun;Zeng Qiang;Cui Tao;Wang Qingmin;Li Dongbo   

  1. Nankai Univ, Elementoorgan Chem Lab.Tianjin(300071)
  • Published:1999-02-15

Thirteen titled compounds were synthesized by the reaction of O- alkyl-O-aryl phosphochloridothioates with 3-(triphenyllgermyl)-1- propanols. Their structures were confirmed by IR, ^1H NMR, MS and elementary analyses. The reaction can be accelerated by addition of phase transfer catalysts and the best results were obtained in the presence of 18-crown-6. Some of these compounds showed antitumor activities in vitro.

Key words: THIOPHOSPHATE, GERMANE, BIOLOGICAL ACTIVITY

CLC Number: