Acta Chimica Sinica ›› 1993, Vol. 51 ›› Issue (11): 1094-1098. Previous Articles     Next Articles

Original Articles

用于癌症病人初级临床诊断的化学计量学研究

王小如;朱尔一;颜晓梅;杨 原;黄本立;庄峙厦   

  1. 厦门大学化学系分析研究所;厦门大学环境科学研究中心
  • 发布日期:1993-11-15

Chemometrics study on preliminary clinical diagnostics for cancer patients

WANG XIAORU;ZHU ERYI;YAN XIAOMEI;YANG;HUANG BENLI;ZHUANG SHUIXIA   

  • Published:1993-11-15

Multielements in normal people's and cancer patient's hair and serum samples were simultaneously determine with inductively coupled plasma-at. emission spectrometry (ICP-AES). The trace amount of Se in hair and serum was determine with a graphite furnace atomic absorption spectrometer (GF-AAS). The experimental results obtained were then studied with the chemometric technique. Both partial least squares (PLS) and Gram-Schmid methods were applied to the classification of normal people and cancer patients. The technique developed is considered to be used as a preliminary clin. diagnostic method for cancer patients. Hair samples are preferred as the analyte due to their easy sampling, treatment, storage as well as transportation.

Key words: DIAGNOSIS, ATOMIC ABSORPTION SPECTROPHOTOMETRY, CARCINOMA, HUMAN HAIR, GRAPHITIZING FURNACES, SERUM, ICP, ATOMIC EMISSION SPECTROMETRY, STOICHIOMETRY

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