The syntheses of some 3-substituted-5-hydrozy-6-methyl-1,2,4-triazines (1) are reported.The oxidation of 3-methylthio-5-hydrogy-6-methyl-1,2,4-triazine (3) with potassium permanganate at room temperature in aqueous sodium hydroxide solution yielded 3-methylsulfon-5-hydroxy-6-methyl-1,2,4-triazine (13) which reacted with nudeophilio reagents (e.g.ammonia,hydrazine hydrate,P-toluidine,isobutylamine,piperidine,sodium ethoxi.de,sodium phenoxide) under mild conditions to give the corresponding 3-amino-5-hydroxy-6-methyl-1,2,4-triazine (6),3-hydrazine-5-hydroxy-6-methyl-1,2,4-triazine (7),3-P-toluidino-5-hydroxy-6-methyl-1,2,4-triazine (8),3-iso-butylamino-5-hydroxy-6-methyl-1,2,4-triazine(9),3-piperidino-5-hydroxyl-methyl-1,2,4-triazine (10),3-ethoxy-5-hydroxy-6-methyl-1,2,4-triazine (11) and 3-phenoxy-5-hydroxy-6-methyl-1,2,4-triazine (12).