Chin. J. Org. Chem. ›› 2015, Vol. 35 ›› Issue (1): 228-231.DOI: 10.6023/cjoc201407003 Previous Articles     Next Articles



刘世娟, 马文兵, 郑志花, 马忠平, 曹端林   

  1. 中北大学化工与环境学院 太原 030051
  • 收稿日期:2014-07-02 修回日期:2014-09-03 发布日期:2014-09-18
  • 通讯作者: 马文兵, 曹端林;

Palladium-Catalyzed Synthesis of 2-Hydroxyphenyl Vinylferrocene

Liu Shijuan, Ma Wenbing, Zheng Zhihua, Ma Zhongping, Cao Duanlin   

  1. School of Chemical and Environmental Engineering, North University of China, Taiyuan 030051
  • Received:2014-07-02 Revised:2014-09-03 Published:2014-09-18

A Pd-catalyzed method was developed for Heck-type cross-coupling reaction of a wide range of o-iodo(bromo)- phenols with vinylferrocene. The influences of different palladium catalyst, bases, solvents and other conditions were investigated. In the presence of PdCl2(dppf), Cs2CO3 and CH3CN, the cross-coupling products can be obtained in moderate to good yields. This catalyst system exhibits good activity in the synthesis of o-hydroxyphenyl vinylferrocene compounds.

Key words: Heck-type cross-coupling reaction, vinylferrocene, o-iodo(bromo)phenols, palladium-catalyzed