Palladium-Catalyzed Intramolecular [4+2] Cycloadition Reactions of Aryl-Substituted Diynes

doi:10.6023/cjoc201505032

Chin. J. Org. Chem. ›› 2015, Vol. 35 ›› Issue (11): 2333-2339.DOI: 10.6023/cjoc201505032 Previous Articles Next Articles

Articles

钯催化芳基取代二炔分子内[4+2]环化反应

吴玉芹^a, 杨永^b, 李立冬^a

a 盐城工学院化学化工学院盐城 224051;
b 盐城第二人民医院盐城 224003

收稿日期:2015-05-20 修回日期:2015-06-23 发布日期:2015-07-10
通讯作者: 李立冬 E-mail:ld-l@163.com
基金资助:
国家自然科学基金(No. 21272005)资助项目.

Palladium-Catalyzed Intramolecular [4+2] Cycloadition Reactions of Aryl-Substituted Diynes

Wu Yuqin^a, Yang Yong^b, Li Lidong^a

a School of Chemistry and Chemical Engineering, Yancheng Institute of Technology, Yancheng 224051;
b The Second People's Hospital of Yancheng, Yancheng 224003

Received:2015-05-20 Revised:2015-06-23 Published:2015-07-10
Supported by:
Project supported by the National Natural Science Foundation of China (No. 21272005).

1. Palladium-Catalyzed Intramolecular [4+2] Cycloadition Reactions of Aryl-Substituted Diynes.PDF(275KB)

Abstract

The nitrogen-containing heterocyclic compounds are important organic molecules which could be widely found in nature. Most of them have biologic activity and become the core skeleton of agrochemicals, pharmaceuticals, dyes and organic functional materials. A practical and efficient domino method for the preparation of diversely fused yne-functionalized benzoisoindole from triynes is developed via palladium-catalyzed [4+2] cycloaddition. All new products were fully characterized by various spectroscopic techniques and high-resolution mass spectrometry. The molecular structure of 2g was confirmed using single-crystal X-ray analyses.

Key words: palladium-catalyzed, synthesis, C-C coupling, benzoisoindole derivatives

Cite this article

Wu Yuqin, Yang Yong, Li Lidong. Palladium-Catalyzed Intramolecular [4+2] Cycloadition Reactions of Aryl-Substituted Diynes[J]. Chin. J. Org. Chem., 2015, 35(11): 2333-2339.

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钯催化芳基取代二炔分子内[4+2]环化反应

Palladium-Catalyzed Intramolecular [4+2] Cycloadition Reactions of Aryl-Substituted Diynes

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