Chin. J. Org. Chem. ›› 2014, Vol. 34 ›› Issue (12): 2438-2447.DOI: 10.6023/cjoc201407027 Previous Articles     Next Articles



徐四龙a, 贺峥杰b   

  1. a. 西安交通大学理学院化学系 西安 710049;
    b. 南开大学元素有机化学国家重点实验室 天津化学化工协同创新中心 天津 300071
  • 收稿日期:2014-07-16 修回日期:2014-08-11 发布日期:2014-08-26
  • 通讯作者: 贺峥杰
  • 基金资助:


Progress on Vinylogous Organic Reactions of Allylic Phosphorus Ylides with Carbonyl Compounds

Xu Silonga, He Zhengjieb   

  1. a. Department of Chemistry, School of Science, Xi'an Jiaotong University, Xi'an 710049;
    b. State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Collaborative Innovation Center of Chemical Science and Engineering, Tianjin 300071
  • Received:2014-07-16 Revised:2014-08-11 Published:2014-08-26
  • Supported by:

    Project supported by the National Natural Science Foundation of China (Nos. 21272119, 21121002), the Research Fund for the Doctoral Program of Higher Education of China (No. 20110031110012), the Fundamental Research Funds for the Central Universities (No. 08143076) and the China Postdoctoral Science Foundation (No. 2014M550484).

Allylic phosphorus ylides are a class of important and versatile intermediates in synthetic organic chemistry. Due to the delocalization of the carbanion center, an array of vinylogous organic reactions of allylic phosphorus ylides through γ-attack of the carbanion have been achieved in recent years. This mini-review aims to summarize the vinylogous reactivity of allylic phosphorus ylides toward carbonyl compounds, mainly including vinylogous Wittig reactions and various annulation reactions. These reactions broaden the application of allylic phosphorus ylides in organic chemistry, and also provide new synthetic methods for many important organic molecules.

Key words: phosphorus ylide, vinylogy, Wittig reaction, annulation reaction