Chin. J. Org. Chem. ›› 2015, Vol. 35 ›› Issue (3): 712-718.DOI: 10.6023/cjoc201409044 Previous Articles     Next Articles



孟团结a,b, 黄现强a, 王进贤a, 辛丽a   

  1. a 西北师范大学化学化工学院 兰州 730070;
    b 商丘师范学院化学化工学院 有机新材料合成重点实验室 商丘 476000
  • 收稿日期:2014-09-26 修回日期:2014-10-02 发布日期:2014-11-13
  • 通讯作者: 孟团结, 王进贤;
  • 基金资助:

    国家自然科学基金(No. U1204204)资助项目.

Synthesis of Esters via Barbier Reaction Mediated by Zinc Copper Couple under Solvent-Free Conditions

Meng Tuanjiea,b, Huang Xianqianga, Wang Jin-Xiana, Xin Lia   

  1. a College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070;
    b Key Laboratory of New Organic Materials synthesis, College of Chemistry and Chemical Engineering, Shangqiu Normal University, Shangqiu 476000
  • Received:2014-09-26 Revised:2014-10-02 Published:2014-11-13
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. U1204204).

A series of homoallyl esters, homopropargyl esters and β-acetoxyl esters were obtained via Barbier reaction from one pot three component reaction of aldehydes, bromohydrocarbons and anhydrides mediated by zinc copper couple under non-catalytic and solvent-free conditions. The studies on the reaction conditions and the reaction mechanism were also carried out. This protocol has advantages of mild conditions, simple work-up, high yield, easily available starting materials and fast reaction rate.

Key words: Barbier reaction, zinc copper couple, one-pot, solvent-free