Domino Synthesis of Novel Chromene-Indanedione Derivatives

doi:10.6023/cjoc201408032

Chin. J. Org. Chem. ›› 2015, Vol. 35 ›› Issue (3): 719-723.DOI: 10.6023/cjoc201408032 Previous Articles Next Articles

ARTICLE

串联合成新型色烯-茚二酮类化合物

饶寅, 刘美林, 殷国栋

湖北师范学院化学化工学院稀有金属化学湖北省协同创新中心黄石 435002

收稿日期:2014-08-27 修回日期:2014-10-24 发布日期:2014-11-07
通讯作者: 殷国栋 E-mail:gdyin_hbnu@163.com,gdyin@hbnu.edu.cn
基金资助:
湖北省教育厅重点项目基金(No. D20142501)和国家自然科学基金(No. 21102042)资助项目.

Domino Synthesis of Novel Chromene-Indanedione Derivatives

Rao Yin, Liu Meilin, Yin Guodong

Hubei Collaborative Innovation Center for Rare Metal Chemistry, College of Chemistry and Chemical Engineering, Hubei Normal University, Huangshi 435002

Received:2014-08-27 Revised:2014-10-24 Published:2014-11-07
Supported by:
Project supported by the Educational Commission of Hubei Province (No. D20142501) and the National Natural Science Foundation of China (No. 21102042).

1. Domino Synthesis of Novel Chromene-Indanedione Derivatives.PDF(715KB)

Abstract

A simple method for the synthesis of novel chromene-indanedione derivatives (3) has been developed by the reaction of 2-hydroxychalcones (1) with 1,3-indanedione (2) in reflux toluene under catalyst-free conditions. All the compounds were characterized by means of ¹H NMR, ¹³C NMR, IR and HRMS. This reaction probably underwent a domino Michael addition/cyclization/oxidation process. The UV-Vis spectroscopy indicated that the maximum absorption wavelengths of the products 3a～3h were at the range of 464～482 nm.

Key words: chromene, 1,3-indanedione, 2-hydroxychalcones, domino reaction

Cite this article

Rao Yin, Liu Meilin, Yin Guodong. Domino Synthesis of Novel Chromene-Indanedione Derivatives[J]. Chin. J. Org. Chem., 2015, 35(3): 719-723.

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串联合成新型色烯-茚二酮类化合物

Domino Synthesis of Novel Chromene-Indanedione Derivatives

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