Chin. J. Org. Chem. ›› 2015, Vol. 35 ›› Issue (4): 770-780.DOI: 10.6023/cjoc201411041 Previous Articles     Next Articles



吴春蕊a, 杨玉坡b, 史峰a   

  1. a 河南大学 河南省天然药物与免疫工程重点实验室 开封 475004;
    b 青岛科技大学化学与分子工程学院 青岛 266042
  • 收稿日期:2014-11-26 修回日期:2014-12-15 发布日期:2015-01-09
  • 通讯作者: 史峰
  • 基金资助:

    国家自然科学基金(No. 21002021)和河南省高校科技创新人才支持计划基金(No. 13HASTIT010)资助项目.

Recent Advances in Aryne Double Bond Insertion

Wu Chunruia, Yang Yupob, Shi Fenga   

  1. a Key Laboratory of Natural Medicine and Immuno-Engineering of Henan Province, Henan University, Kaifeng 475004;
    b College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042
  • Received:2014-11-26 Revised:2014-12-15 Published:2015-01-09
  • Supported by:

    Project supported by National Natural Science Foundation of China (No. 21002021) and the Program for Science & Technology Innovation Talents in Universities of Henan Province (No. 13HASTIT010).

Aryne double bond insertion generates an ortho-quinomethide-typed intermediate, which, like aryne itself, is one of the most important reactive intermediates in organic reactions. This review summarizes recent advances in this field and the potential applications in synthetic organic chemistry, with a focus on the reaction mechanism, as well as the structure and reactivity of the ortho-quinomethide intermediates.

Key words: aryne, ortho-quinomethide, reactive intermediate, pericyclic reaction, tandem reaction