Chin. J. Org. Chem. ›› 2017, Vol. 37 ›› Issue (8): 1924-1938.DOI: 10.6023/cjoc201703034 Previous Articles     Next Articles



戴小强, 朱亚波, 汪洲洋, 翁建全   

  1. 浙江工业大学化学工程学院 杭州 310014
  • 收稿日期:2017-03-20 修回日期:2017-04-09 发布日期:2017-05-04
  • 通讯作者: 翁建全
  • 基金资助:


Progress in 2-Position Functionalized Synthesis of 2-Substitutedbenzothiazoles

Dai Xiaoqiang, Zhu Yabo, Wang Zhouyang, Weng Jianquan   

  1. College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014
  • Received:2017-03-20 Revised:2017-04-09 Published:2017-05-04
  • Contact: 10.6023/cjoc201703034
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 30900959) and the Natural Science Foundation of Zhejiang Province (No. LY17C140003).

2-Substitutedbenzothiazole derivatives were widely used in chemical, pharmaceutical and agricultural fields. 2-Position functionalized method was a convenient and effective way to synthesize 2-substitutedbenzothiazoles. In this paper, the methods for the synthesis of 2-substitutedbenzothiazoles by the alkylation, acylation, arylation, amination and phosphorylation reactions at the 2-position are reviewed, and their future outlook is also discussed.

Key words: benzothiazole, 2-position functionalization, alkylation, acylation, arylation, amination, phosphorylation