Chin. J. Org. Chem. ›› 2019, Vol. 39 ›› Issue (2): 456-462.DOI: 10.6023/cjoc201807040 Previous Articles     Next Articles



黄锦, 付荣辉, 敬林海, 秦大斌, 黄昆, 汪伟   

  1. 西华师范大学化学化工学院应用化学研究所 化学合成与污染控制四川省重点实验室 南充 637002
  • 收稿日期:2018-07-23 修回日期:2018-08-29 发布日期:2018-09-18
  • 通讯作者: 汪伟
  • 基金资助:


A Convenient Access to 3-Substituted Benzofuran Derivatives via Palladium Nanoparticles-Catalyzed Intramolecular Heck Reaction

Huang Jin, Fu Ronghui, Jing Linhai, Qin Dabin, Huang Kun, Wang Wei   

  1. Chemical Synthesis Pollution Control Key Laboratory of Sichuan Province, Institute of Applied Chemistry, College of Chemistry and Chemical Engineering, China West Normal University, Nanchong 637002
  • Received:2018-07-23 Revised:2018-08-29 Published:2018-09-18
  • Contact: 10.6023/cjoc201807040
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 21602144), and the Science and Technology Program of Sichuan Province (No. 2018JY0485).

A concise and efficiently route for the synthesis of 3-substituted benzofurans via the intramolecular Heck reaction of bromoaryl 3-phenylallyl ethers has been developed. This simple and highly efficient palladium nanoparticles-catalyzed system showed good catalytic activity. The desired products were affored in good to high yields (45%~96%).

Key words: benzofuran, intramolecular Heck reaction, palladium nanoparticles