Chinese Journal of Organic Chemistry ›› 2019, Vol. 39 ›› Issue (10): 2920-2929.DOI: 10.6023/cjoc201903073 Previous Articles     Next Articles



李鹏飞, 黄丹凤, 杨天宇, 邓周斌, 王克虎, 王君姣, 苏瀛鹏, 胡雨来*()   

  1. 西北师范大学化学化工学院 兰州 730070
  • 收稿日期:2019-03-29 修回日期:2019-04-26 发布日期:2019-05-21
  • 通讯作者: 胡雨来
  • 基金资助:
    国家自然科学基金(Nos. 21662030);国家自然科学基金(21861033)

Synthesis of Pyrazolines by Cascade Oxidation/Halogenoamino-cyclization Reaction of Homoallylhydrazides

Li, Pengfei, Huang, Danfeng, Yang, Tianyu, Deng, Zhoubin, Wang, Kehu, Wang, Junjiao, Su, Yingpeng, Hu, Yulai*()   

  1. College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070
  • Received:2019-03-29 Revised:2019-04-26 Published:2019-05-21
  • Contact: Hu, Yulai
  • Supported by:
    Project supported by the National Natural Science Foundation of China(Nos. 21662030);Project supported by the National Natural Science Foundation of China(21861033)

An efficient cascade oxidation/halogenoaminocyclization reaction of homoallylhydrazides with N-halogensuc- cinimide was developed without addition of other additives under mild reaction conditions to provide pyrazolines. Under the optimized conditions, a variety of highly substituted pyrazoline derivatives were obtained.

Key words: oxidation/halogenoaminocyclization, pyrazolines, homoallylhydrazides, N-halogensuccinimide