Chinese Journal of Organic Chemistry ›› 2019, Vol. 39 ›› Issue (10): 2930-2935.DOI: 10.6023/cjoc201904006 Previous Articles Next Articles
ARTICLES
收稿日期:
2019-04-02
修回日期:
2019-04-26
发布日期:
2019-05-21
通讯作者:
于晓强
E-mail:yuxiaoqiang@dlut.edu.cn
基金资助:
Yin, Qing, Yu, Xiaoqiang*(), Bao, Ming
Received:
2019-04-02
Revised:
2019-04-26
Published:
2019-05-21
Contact:
Yu, Xiaoqiang
E-mail:yuxiaoqiang@dlut.edu.cn
Supported by:
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Yin, Qing, Yu, Xiaoqiang, Bao, Ming. A Novel Method for the Synthesis Triarylphosphines under Transition-Metal-Free Conditions[J]. Chinese Journal of Organic Chemistry, 2019, 39(10): 2930-2935.
Entry | Base | Solvent | Yieldb/% |
---|---|---|---|
1 | Cs2CO3 | DMSO | 39 |
2 | K2CO3 | DMSO | NRc |
3 | KOAc | DMSO | NRc |
4 | K3PO4 | DMSO | 45 |
5 | tBuONa | DMSO | 50 |
6 | tBuOK | DMSO | 70 |
7 | Pyridine | DMSO | 23 |
8 | Et3N | DMSO | 42 |
9 | TMEDA | DMSO | 29 |
10 | 2,2'-bpy | DMSO | 30 |
11 | tBuOK | DMF | Trace |
12 | tBuOK | DMAc | 33 |
13 | tBuOK | NMP | Trace |
14 | tBuOK | HMPA | NRc |
15 | tBuOK | Tolune | NRc |
16 | tBuOK | 1,4-Dioxane | NRc |
Entry | Base | Solvent | Yieldb/% |
---|---|---|---|
1 | Cs2CO3 | DMSO | 39 |
2 | K2CO3 | DMSO | NRc |
3 | KOAc | DMSO | NRc |
4 | K3PO4 | DMSO | 45 |
5 | tBuONa | DMSO | 50 |
6 | tBuOK | DMSO | 70 |
7 | Pyridine | DMSO | 23 |
8 | Et3N | DMSO | 42 |
9 | TMEDA | DMSO | 29 |
10 | 2,2'-bpy | DMSO | 30 |
11 | tBuOK | DMF | Trace |
12 | tBuOK | DMAc | 33 |
13 | tBuOK | NMP | Trace |
14 | tBuOK | HMPA | NRc |
15 | tBuOK | Tolune | NRc |
16 | tBuOK | 1,4-Dioxane | NRc |
Entry | Aryl halide 2 | Product 3 | Yieldb/% | Entry | Aryl halide 2 | Product 3 | Yieldb/% |
---|---|---|---|---|---|---|---|
1 | 70 | 10 | 71 | ||||
2 | 77 | 11 | 80 | ||||
3 | 53 | 12 | 60 | ||||
4 | 48 | 13 | 55 | ||||
5 | 40 | 14 | 64 | ||||
6 | 47 | 15 | 50 | ||||
7 | NRc | 16 | NRc | ||||
8 | NRc | 17 | 57 | ||||
9 | 53 |
Entry | Aryl halide 2 | Product 3 | Yieldb/% | Entry | Aryl halide 2 | Product 3 | Yieldb/% |
---|---|---|---|---|---|---|---|
1 | 70 | 10 | 71 | ||||
2 | 77 | 11 | 80 | ||||
3 | 53 | 12 | 60 | ||||
4 | 48 | 13 | 55 | ||||
5 | 40 | 14 | 64 | ||||
6 | 47 | 15 | 50 | ||||
7 | NRc | 16 | NRc | ||||
8 | NRc | 17 | 57 | ||||
9 | 53 |
Entry | Phosphorus source 1 | Aryl halide 2 | Product 3 | Yieldb/% | Entry | Phosphorus source 1 | Aryl halide 2 | Product 3 | Yieldb/% |
---|---|---|---|---|---|---|---|---|---|
1 | 2a | 3a | 46 | 7 | 2a | 3a | 44 | ||
2 | 2b | 3b | 53 | 8 | 2b | 3b | 47 | ||
3 | 2c | 3c | 40 | 9 | 2c | 3c | 40 | ||
4 | 2a | 3a | 36 | 10 | 2a | — | NRc | ||
5 | 2b | 3b | 40 | 11 | 2b | — | NRc | ||
6 | 2c | 3c | 30 | 12 | 2c | — | NRc |
Entry | Phosphorus source 1 | Aryl halide 2 | Product 3 | Yieldb/% | Entry | Phosphorus source 1 | Aryl halide 2 | Product 3 | Yieldb/% |
---|---|---|---|---|---|---|---|---|---|
1 | 2a | 3a | 46 | 7 | 2a | 3a | 44 | ||
2 | 2b | 3b | 53 | 8 | 2b | 3b | 47 | ||
3 | 2c | 3c | 40 | 9 | 2c | 3c | 40 | ||
4 | 2a | 3a | 36 | 10 | 2a | — | NRc | ||
5 | 2b | 3b | 40 | 11 | 2b | — | NRc | ||
6 | 2c | 3c | 30 | 12 | 2c | — | NRc |
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doi: 10.1007/BF01185936 |
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