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Chin. J. Org. Chem. ›› 2006, Vol. 26 ›› Issue (07): 988-991. Previous Articles Next Articles
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张新歌，李朝兴*，张慧杰，汤宇，王瑱
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ZHANG Xin-Ge,LI Chao-Xing*,ZHANG Hui-Jie,TANG Yu,WANG Zhen
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A novel class of chiral phase transfer catalysts was synthesized conveniently from cinchona alkaloids and 2-(chloromethyl)benzimidazole. Using these new catalysts (10 mol%), enantioselective alkylations of N-(diphenylmethylene)glycine tert-butyl ester were efficiently carried out with various alkyl halides, and the chemical yields were up to 85% with the ee of the products up to 95%.
Key words: chiral phase transfer catalyst, cinchona alkaloid, enantioselective alkylation
ZHANG Xin-Ge,LI Chao-Xing*,ZHANG Hui-Jie,TANG Yu,WANG Zhen. Synthesis of 4-(4-{5-[(Dibenzylcarbamoyl)-methyl]-2-heptyl-4-oxo-thiazolidin-3-yl}-butyl)-benzoic Acid[J]. Chin. J. Org. Chem., 2006, 26(07): 988-991.
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