It was recently reported^[1] that elucosamine (2-amino-2-deoxy-D-glucopyranose) reduced the rate of glycolysis of scbisiosoma mansoni and its G-phosphate inhibited the glucokinase action of the parasite, and that the reduction of the survival of the parasite by glucosamine was observed both in vitro and n vivo. Some new glucosamine derivatives, which may serve as potential intermediates for the preparation of chemotherapeutic agents against schistosomiasis, have there fore been synthesized.